Search | VHL CLAP/WR-PAHO/WHO

1.

A mouse DRG genetic toolkit reveals morphological and physiological diversity of somatosensory neuron subtypes.

Qi, Lijun; Iskols, Michael; Shi, David; Reddy, Pranav; Walker, Christopher; Lezgiyeva, Karina; Voisin, Tiphaine; Pawlak, Mathias; Kuchroo, Vijay K; Chiu, Isaac M; Ginty, David D; Sharma, Nikhil.

Cell ; 187(6): 1508-1526.e16, 2024 Mar 14.

Article in English | MEDLINE | ID: mdl-38442711

2.

Charting the cellular biogeography in colitis reveals fibroblast trajectories and coordinated spatial remodeling.

Cadinu, Paolo; Sivanathan, Kisha N; Misra, Aditya; Xu, Rosalind J; Mangani, Davide; Yang, Evan; Rone, Joseph M; Tooley, Katherine; Kye, Yoon-Chul; Bod, Lloyd; Geistlinger, Ludwig; Lee, Tyrone; Mertens, Randall T; Ono, Noriaki; Wang, Gang; Sanmarco, Liliana; Quintana, Francisco J; Anderson, Ana C; Kuchroo, Vijay K; Moffitt, Jeffrey R; Nowarski, Roni.

Cell ; 187(8): 2010-2028.e30, 2024 Apr 11.

Article in English | MEDLINE | ID: mdl-38569542

3.

Stem-like intestinal Th17 cells give rise to pathogenic effector T cells during autoimmunity.

Schnell, Alexandra; Huang, Linglin; Singer, Meromit; Singaraju, Anvita; Barilla, Rocky M; Regan, Brianna M L; Bollhagen, Alina; Thakore, Pratiksha I; Dionne, Danielle; Delorey, Toni M; Pawlak, Mathias; Meyer Zu Horste, Gerd; Rozenblatt-Rosen, Orit; Irizarry, Rafael A; Regev, Aviv; Kuchroo, Vijay K.

Cell ; 184(26): 6281-6298.e23, 2021 12 22.

Article in English | MEDLINE | ID: mdl-34875227

4.

Polyamine metabolism is a central determinant of helper T cell lineage fidelity.

Puleston, Daniel J; Baixauli, Francesc; Sanin, David E; Edwards-Hicks, Joy; Villa, Matteo; Kabat, Agnieszka M; Kaminski, Marcin M; Stanckzak, Michal; Weiss, Hauke J; Grzes, Katarzyna M; Piletic, Klara; Field, Cameron S; Corrado, Mauro; Haessler, Fabian; Wang, Chao; Musa, Yaarub; Schimmelpfennig, Lena; Flachsmann, Lea; Mittler, Gerhard; Yosef, Nir; Kuchroo, Vijay K; Buescher, Joerg M; Balabanov, Stefan; Pearce, Edward J; Green, Douglas R; Pearce, Erika L.

Cell ; 184(16): 4186-4202.e20, 2021 08 05.

Article in English | MEDLINE | ID: mdl-34216540

5.

Metabolic modeling of single Th17 cells reveals regulators of autoimmunity.

Wagner, Allon; Wang, Chao; Fessler, Johannes; DeTomaso, David; Avila-Pacheco, Julian; Kaminski, James; Zaghouani, Sarah; Christian, Elena; Thakore, Pratiksha; Schellhaass, Brandon; Akama-Garren, Elliot; Pierce, Kerry; Singh, Vasundhara; Ron-Harel, Noga; Douglas, Vivian Paraskevi; Bod, Lloyd; Schnell, Alexandra; Puleston, Daniel; Sobel, Raymond A; Haigis, Marcia; Pearce, Erika L; Soleimani, Manoocher; Clish, Clary; Regev, Aviv; Kuchroo, Vijay K; Yosef, Nir.

Cell ; 184(16): 4168-4185.e21, 2021 08 05.

Article in English | MEDLINE | ID: mdl-34216539

6.

T_H17 cell heterogeneity and its role in tissue inflammation.

Schnell, Alexandra; Littman, Dan R; Kuchroo, Vijay K.

Nat Immunol ; 24(1): 19-29, 2023 01.

Article in English | MEDLINE | ID: mdl-36596896

7.

Targeting PGLYRP1 promotes antitumor immunity while inhibiting autoimmune neuroinflammation.

Schnell, Alexandra; Huang, Linglin; Regan, Brianna M L; Singh, Vasundhara; Vonficht, Dominik; Bollhagen, Alina; Wang, Mona; Hou, Yu; Bod, Lloyd; Sobel, Raymond A; Chihara, Norio; Madi, Asaf; Anderson, Ana C; Regev, Aviv; Kuchroo, Vijay K.

Nat Immunol ; 24(11): 1908-1920, 2023 Nov.

Article in English | MEDLINE | ID: mdl-37828379

8.

Gut-Innervating Nociceptor Neurons Regulate Peyer's Patch Microfold Cells and SFB Levels to Mediate Salmonella Host Defense.

Lai, Nicole Y; Musser, Melissa A; Pinho-Ribeiro, Felipe A; Baral, Pankaj; Jacobson, Amanda; Ma, Pingchuan; Potts, David E; Chen, Zuojia; Paik, Donggi; Soualhi, Salima; Yan, Yiqing; Misra, Aditya; Goldstein, Kaitlin; Lagomarsino, Valentina N; Nordstrom, Anja; Sivanathan, Kisha N; Wallrapp, Antonia; Kuchroo, Vijay K; Nowarski, Roni; Starnbach, Michael N; Shi, Hailian; Surana, Neeraj K; An, Dingding; Wu, Chuan; Huh, Jun R; Rao, Meenakshi; Chiu, Isaac M.

Cell ; 180(1): 33-49.e22, 2020 01 09.

Article in English | MEDLINE | ID: mdl-31813624

9.

Type I interferon transcriptional network regulates expression of coinhibitory receptors in human T cells.

Sumida, Tomokazu S; Dulberg, Shai; Schupp, Jonas C; Lincoln, Matthew R; Stillwell, Helen A; Axisa, Pierre-Paul; Comi, Michela; Unterman, Avraham; Kaminski, Naftali; Madi, Asaf; Kuchroo, Vijay K; Hafler, David A.

Nat Immunol ; 23(4): 632-642, 2022 04.

Article in English | MEDLINE | ID: mdl-35301508

10.

LAG-3, TIM-3, and TIGIT: Distinct functions in immune regulation.

Joller, Nicole; Anderson, Ana C; Kuchroo, Vijay K.

Immunity ; 57(2): 206-222, 2024 Feb 13.

Article in English | MEDLINE | ID: mdl-38354701

11.

Endoplasmic reticulum stress in the intestinal epithelium initiates purine metabolite synthesis and promotes Th17 cell differentiation in the gut.

Duan, Jinzhi; Matute, Juan D; Unger, Lukas W; Hanley, Thomas; Schnell, Alexandra; Lin, Xi; Krupka, Niklas; Griebel, Paul; Lambden, Conner; Sit, Brandon; Grootjans, Joep; Pyzik, Michal; Sommer, Felix; Kaiser, Sina; Falk-Paulsen, Maren; Grasberger, Helmut; Kao, John Y; Fuhrer, Tobias; Li, Hai; Paik, Donggi; Lee, Yunjin; Refetoff, Samuel; Glickman, Jonathan N; Paton, Adrienne W; Bry, Lynn; Paton, James C; Sauer, Uwe; Macpherson, Andrew J; Rosenstiel, Philip; Kuchroo, Vijay K; Waldor, Matthew K; Huh, Jun R; Kaser, Arthur; Blumberg, Richard S.

Immunity ; 56(5): 1115-1131.e9, 2023 05 09.

Article in English | MEDLINE | ID: mdl-36917985

12.

Publisher Correction: An immunoregulatory and tissue-residency program modulated by c-MAF in human T_H17 cells.

Aschenbrenner, Dominik; Foglierini, Mathilde; Jarrossay, David; Hu, Dan; Weiner, Howard L; Kuchroo, Vijay K; Lanzavecchia, Antonio; Notarbartolo, Samuele; Sallusto, Federica.

Nat Immunol ; 20(1): 109, 2019 01.

Article in English | MEDLINE | ID: mdl-30448856

13.

Follicular regulatory T cells control humoral and allergic immunity by restraining early B cell responses.

Clement, Rachel L; Daccache, Joe; Mohammed, Mostafa T; Diallo, Alos; Blazar, Bruce R; Kuchroo, Vijay K; Lovitch, Scott B; Sharpe, Arlene H; Sage, Peter T.

Nat Immunol ; 20(10): 1360-1371, 2019 10.

Article in English | MEDLINE | ID: mdl-31477921

14.

How does Epstein-Barr virus trigger MS?

Kuchroo, Vijay K; Weiner, Howard L.

Immunity ; 55(3): 390-392, 2022 03 08.

Article in English | MEDLINE | ID: mdl-35263566

15.

Disruption of the IL-33-ST2-AKT signaling axis impairs neurodevelopment by inhibiting microglial metabolic adaptation and phagocytic function.

He, Danyang; Xu, Heping; Zhang, Huiyuan; Tang, Ruihan; Lan, Yangning; Xing, Ruxiao; Li, Shaomin; Christian, Elena; Hou, Yu; Lorello, Paul; Caldarone, Barbara; Ding, Jiarui; Nguyen, Lan; Dionne, Danielle; Thakore, Pratiksha; Schnell, Alexandra; Huh, Jun R; Rozenblatt-Rosen, Orit; Regev, Aviv; Kuchroo, Vijay K.

Immunity ; 55(1): 159-173.e9, 2022 01 11.

Article in English | MEDLINE | ID: mdl-34982959

16.

Induction of a colitogenic phenotype in Th1-like cells depends on interleukin-23 receptor signaling.

Pawlak, Mathias; DeTomaso, David; Schnell, Alexandra; Meyer Zu Horste, Gerd; Lee, Youjin; Nyman, Jackson; Dionne, Danielle; Regan, Brianna M L; Singh, Vasundhara; Delorey, Toni; Schramm, Markus A; Wang, Chao; Wallrapp, Antonia; Burkett, Patrick R; Riesenfeld, Samantha J; Anderson, Ana C; Regev, Aviv; Xavier, Ramnik J; Yosef, Nir; Kuchroo, Vijay K.

Immunity ; 55(9): 1663-1679.e6, 2022 09 13.

Article in English | MEDLINE | ID: mdl-36070768

17.

IL-17 Blockade in Psoriasis.

Burkett, Patrick R; Kuchroo, Vijay K.

Cell ; 167(7): 1669, 2016 Dec 15.

Article in English | MEDLINE | ID: mdl-27984714

18.

A Distinct Gene Module for Dysfunction Uncoupled from Activation in Tumor-Infiltrating T Cells.

Singer, Meromit; Wang, Chao; Cong, Le; Marjanovic, Nemanja D; Kowalczyk, Monika S; Zhang, Huiyuan; Nyman, Jackson; Sakuishi, Kaori; Kurtulus, Sema; Gennert, David; Xia, Junrong; Kwon, John Y H; Nevin, James; Herbst, Rebecca H; Yanai, Itai; Rozenblatt-Rosen, Orit; Kuchroo, Vijay K; Regev, Aviv; Anderson, Ana C.

Cell ; 166(6): 1500-1511.e9, 2016 Sep 08.

Article in English | MEDLINE | ID: mdl-27610572

19.

An immunoregulatory and tissue-residency program modulated by c-MAF in human T_H17 cells.

Aschenbrenner, Dominik; Foglierini, Mathilde; Jarrossay, David; Hu, Dan; Weiner, Howard L; Kuchroo, Vijay K; Lanzavecchia, Antonio; Notarbartolo, Samuele; Sallusto, Federica.

Nat Immunol ; 19(10): 1126-1136, 2018 10.

Article in English | MEDLINE | ID: mdl-30201991

20.

Single-Cell Genomics Unveils Critical Regulators of Th17 Cell Pathogenicity.

Gaublomme, Jellert T; Yosef, Nir; Lee, Youjin; Gertner, Rona S; Yang, Li V; Wu, Chuan; Pandolfi, Pier Paolo; Mak, Tak; Satija, Rahul; Shalek, Alex K; Kuchroo, Vijay K; Park, Hongkun; Regev, Aviv.

Cell ; 163(6): 1400-12, 2015 Dec 03.

Article in English | MEDLINE | ID: mdl-26607794

VHL CLAP/WR-PAHO/WHO

Latin-American Center for Perinatology, Woman and Reproductive Health

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